HapticV1, Main, Exploration, bibRecord, 001330

Current and emerging strategies for treatment of childhood dystonia

Identifieur interne : 001330 ( Main/Exploration ); précédent : 001329; suivant : 001331

Current and emerging strategies for treatment of childhood dystonia

Auteurs : Matteo Bertucco [États-Unis] ; Terence D. Sanger [États-Unis]

Source :

Journal of hand therapy : official journal of the American Society of Hand Therapists [ 0894-1130 ] ; 2014.

RBID : PMC:4424089

Abstract

Childhood dystonia is a movement disorder characterized by involuntary sustained or intermittent muscle contractions causing twisting and repetitive movements, abnormal postures, or both (Sanger et al. 2003). Dystonia is a devastating neurological condition that prevents the acquisition of normal motor skills during critical periods of development in children. Moreover, it is particularly debilitating in children when dystonia affects the upper extremities such that learning and consolidation of common daily motor actions are impeded. Thus, the treatment and rehabilitation of dystonia is a challenge that continuously requires exploration of novel interventions. This review will initially describe the underlying neurophysiological mechanisms of the motor impairments found in childhood dystonia followed by the clinical measurement tools that are available to document the presence and severity of symptoms. Finally, we will discuss the state-of-the-art of therapeutic options for childhood dystonia, with particular emphasis on emergent and innovative strategies.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424089

DOI: 10.1016/j.jht.2014.11.002
PubMed: 25835254
PubMed Central: 4424089

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="P2">Childhood dystonia is a movement disorder characterized by involuntary sustained or intermittent muscle contractions causing twisting and repetitive movements, abnormal postures, or both (Sanger et al. 2003). Dystonia is a devastating neurological condition that prevents the acquisition of normal motor skills during critical periods of development in children. Moreover, it is particularly debilitating in children when dystonia affects the upper extremities such that learning and consolidation of common daily motor actions are impeded. Thus, the treatment and rehabilitation of dystonia is a challenge that continuously requires exploration of novel interventions. This review will initially describe the underlying neurophysiological mechanisms of the motor impairments found in childhood dystonia followed by the clinical measurement tools that are available to document the presence and severity of symptoms. Finally, we will discuss the state-of-the-art of therapeutic options for childhood dystonia, with particular emphasis on emergent and innovative strategies.</p>
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Current and emerging strategies for treatment of childhood dystonia

Current and emerging strategies for treatment of childhood dystonia

Source :

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